Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
TNPO2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
17831-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TNPO2 Fusion Protein Ag12229 (1-350 aa encoded by BC072420)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDWQPDEQG LQQVLQLLKD SQSPNTATQR IVQDKLKQLN QFPDFNNYLI FVLTRLKSED EPTRSLSGLI LKNNVKAHYQ SFPPPVADFI KQECLNNIGD ASSLIRATIG ILITTIASKG ELQMWPELLP QLCNLLNSED YNTCEGAFGA LQKICEDSSE LLDSDALNRP LNIMIPKFLQ FFKHCSPKIR SHAIACVNQF IMDRAQALMD NIDTFIEHLF ALAVDDDPEV RKNVCRALVM LLEVRIDRLI PHMHSIIQYM LQRTQDHDEN VALEACEFWL TLAEQPICKE VLASHLVQLI PILVNGMKYS EIDIILLKGD VEEDEAVPDS EQDIKPRFHK SRTVTLPHEA E (1-350 aa encoded by BC072420)
靶标信息
Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: importin 3; karyopherin (importin) beta 2b; karyopherin beta 2b, transportin; Karyopherin beta-2b; transportin 2 (importin 3, karyopherin beta 2b); Transportin-2
基因别名: 1110034O24Rik; AA414969; AI464345; AI852433; IPO3; Knpb2b; KPNB2B; TNPO2; TRN2
UniProt ID: (Human) O14787, (Mouse) Q99LG2
Entrez Gene ID: (Human) 30000, (Mouse) 212999, (Rat) 304670
