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Invitrogen
USP12 Polyclonal Antibody
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USP12 Antibody (PA5-110554) in WB
Western blot analysis of USP12 in extracts of various cell lines. Samples were incubated with USP12 Polyclonal antibody (Product # PA5-110554) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 2 min.
产品信息
PA5-110554
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human USP12 (NP_8722942)
偶联物
形式
Liquid
浓度
2.79 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MEILMTVSKF ASICTMGANA SALEKEIGPE QFPVNEHYFG LVNFGNTCYC NSVLQALYFC RPFREKVLAY KSQPRKKESL LTCLADLFHS IATQKKKVGV
靶标信息
Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035). [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deubiquitinating enzyme 12; Ubiquitin carboxyl-terminal hydrolase 12; ubiquitin hydrolyzing enzyme 1; Ubiquitin specific peptidase 12; ubiquitin specific protease 12; ubiquitin specific protease 12 like 1; Ubiquitin thioesterase 12; ubiquitin thiolesterase 12; Ubiquitin-hydrolyzing enzyme 1; Ubiquitin-specific-processing protease 12
基因别名: UBH1; USP12; USP12L1
UniProt ID: (Human) O75317, (Rat) D0RB01, (Mouse) Q9D9M2
Entrez Gene ID: (Human) 219333, (Rat) 360763, (Mouse) 22217
