应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
0.04-0.4 µg/mL | - |
免疫组化(石蜡) (IHC (P)) |
1:50-1:200 | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant protein corresponding to Human UBC |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.05 mg/mL |
纯化类型 |
Affinity Chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2790703 |
Immunogen sequence: MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ Q
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Polyubiquitin-C; Ubiquitin
基因别名: HMG20; UBC
UniProt ID: (Human) Q9BX98
Entrez Gene ID: (Human) 7316