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Proteintech
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Sequence of this protein is as follows: DWIWNQMHID EEKNESLPHY VGKIKSNVNR QNAKYVLQGE FAGKIFGVDA NTGNVLAYER LDREKVSEYF LTALIVDKNT NKNLEQPSSF TVKVHDINDN WPVFSHQVFN ASVPEMSAIG TSVIRVTAVD ADDPTVAGHA TVLYQIVKGN EYFSIDNSGL IFTKIKNLDR EKQAEYKIVV ETQDALGLRG ESGTATVMIR LEDINDNFPV FTQSTYTFSV PEDIRVGKPL GFLTVVDPDE PQNRMTKYSI MQGEYRDTFT IETDPKRNEG IIKPTKSLDY EVIQQYTFYI EATDPTIRYE YLSSTSGKNK AMVTINVLDV DEPPVFQRHF YHFKLPENQK KPLIGTVVAK DPDKAQRSIG YSIRKTSDRG QFFRITKQGN IYNEKELDRE TYAWYNLTVE ANELDSRGNP VGKESIVQVY IEVLDENDNP PEFAQPYEPK VCENAAQGKL VVQISATDKD VVPVNPKFKF ALKNEDSNFT LINNHDNTAN ITVKYGQFNR EHAKFHYLPV LISDNGVPSL TGTSTLTVGV CKCNEQGEFT FCEEMAA
VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 7B4/cadherin-5; Cadherin-5; CD144; Vascular endothelial cadherin; VE-cadherin
基因别名: 7B4; AA408225; Cd144; Cdh5; VE-Cad; Vec; VEcad; VECD
UniProt ID: (Mouse) P55284
Entrez Gene ID: (Mouse) 12562, (Rat) 307618