FIGURE: 1 / 2
Peptide sequence: KMDINRRRYP AHLARSSSRK YTELPHGAIS EDQAVGPADI PCDSTGQTST
Sequence homology: Cow: 79%; Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%
The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene.
Protein Aliases: dCTP pyrophosphatase 1; dCTPase 1; Deoxycytidine-triphosphatase 1; RS21C6; XTP3-transactivated gene A protein; XTP3-transactivated protein A
Gene Aliases: CDA03; DCTPP1; RS21C6; XTP3TPA
UniProt ID: (Human) Q9H773
Entrez Gene ID: (Human) 79077