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Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Fez family zinc finger protein 1; Zinc finger protein 312B
基因别名: 3110069A13Rik; FEZ; fez-like; FEZF1; HH22; RGD1560480; Zfp312-like; ZNF312B
UniProt ID: (Human) A0PJY2, (Mouse) Q0VDQ9
Entrez Gene ID: (Human) 389549, (Rat) 500048, (Mouse) 73191