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Invitrogen
eIF2b epsilon Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-84639
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
规格
40 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SILEENVLLG SGTVIGSNCF ITNSVIGPGC HIGDNVVLDQ TYLWQGVRVA AGAQIHQSLL CDNAEVKERV TLKPRSVLTS QVVVGPNITL PEGSVISLHP PD
Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 88%.
靶标信息
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B, a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: eIF-2B GDP-GTP exchange factor subunit epsilon; eIF2B GDP-GTP exchange factor subunit epsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; translation initiation factor eIF-2B subunit epsilon; unnamed protein product
基因别名: CACH; CLE; EIF-2B; EIF2Bepsilon; LVWM; VWM5
UniProt ID: (Human) Q13144
Entrez Gene ID: (Human) 8893
ovarian follicle development
cytoplasmic translational initiation
translational initiation
response to heat
response to glucose
astrocyte development
oligodendrocyte development
hippocampus development
response to endoplasmic reticulum stress
myelination
positive regulation of apoptotic process
response to peptide hormone
positive regulation of translation
positive regulation of translational initiation
astrocyte differentiation
T cell receptor signaling pathway
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