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Canine TIMP-2 quantitates canine TIMP-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine TIMP-2.
TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CSC-21K, DDC8, TIMP2
基因ID : (Dog) 403633, (Human) 7077
基因符号 : TIMP2, TIMP2
蛋白别名 : CSC-21K, Metalloproteinase inhibitor 2, testicular secretory protein Li 57, TIMP 2, TIMP-2, tissue inhibitor of matrix metalloproteinase-2, tissue inhibitor of metalloproteinase-2, Tissue inhibitor of metalloproteinases 2
UniProt ID (Dog) Q9TTY1, (Human) P16035