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Invitrogen
Human IL-1 F6 ELISA Kit
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产品规格
检测灵敏度
0.8 ng/mL
测定范围
0.8-200 ng/mL
检测样本类型/体积
{Supernatant=50 µL, Plasma=50 µL, Serum=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
IL1F6
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human IL-1 F6 quantitates human IL-1 F6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-1 F6.
靶标信息
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36alpha (IL-1F6), beta (IL-1F8), and gamma (IL-1F9). IL-36alpha is highly expressed in psoriatic plaques, as are IL-36beta and IL-36gamma, and is the only IL-1 family member found to be expressed by T cells, as well as monocytes and B cells. Primarily found in skin and lymphoid tissues, IL-36alpha is also found to a lesser extent in tissues of the fetal brain, trachea, stomach, and intestine. IL-36alpha signals through a combination of the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells, and the widely expressed IL-RAcP (IL-1 receptor accessory protein). IL-36alpha also functions as an agonist of NF-kappaB and MAPK pathways, and induces the production of proinflammatory cytokines and chemokines, including IL-6, IL-8, BD-2, and BD-3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), IL1E, IL1F6, IL36A
基因ID : (Human) 27179
基因符号 : IL36A
蛋白别名 : FIL1 epsilon, IL-1 epsilon, IL-1F6, IL-1F6 (FIL-1-epsilon), interleukin 1 family, member 6 (epsilon), interleukin 1, epsilon, Interleukin, Interleukin-36, Interleukin-1 epsilon, Interleukin-1 family member 6, Interleukin-36 alpha
UniProt ID (Human) Q9UHA7
