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Invitrogen
Human LRRC4 ELISA Kit
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产品规格
检测灵敏度
0.42 ng/mL
测定范围
0.42-100 ng/mL
检测样本类型/体积
{Supernatant=50 µL, Serum=50 µL, Plasma=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
LRRC4
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human LRRC4 quantitates human LRRC4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human LRRC4.
靶标信息
The LRRC4 gene, also known as netrin-G ligand 2 (NGL-2), is a brain-specific member of the leucine-rich repeat superfamily, playing a critical role in the central nervous system. Its expression is particularly high in areas such as the hippocampal CA1 and CA2 regions, as well as in granule cells of the dentate gyrus. LRRC4 is a known tumor suppressor gene associated with glioma suppression, as it regulates glioma cell growth, angiogenesis, and invasion through extensive signaling networks. It can participate in multiphase loops involving miRNA, transcription factors, and gene methylation modifications. This gene targets various genes involved in cell motility, impacting glioblastoma cell movement and polarization by binding to enhancer elements and activating transcription, notably the RAP1GAP gene. Its function and expression are crucial in maintaining normal brain function and hold potential implications in the management of gliomagenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : BAG, LRRC4, NAG14, NGL-2, UNQ554/PRO1111
基因ID : (Human) 64101
基因符号 : LRRC4
蛋白别名 : brain tumor associated protein LRRC4, Brain tumor-associated protein BAG, leucine-rich repeat-containing 4, Leucine-rich repeat-containing protein 4, Nasopharyngeal carcinoma-associated gene 14 protein, Netrin-G2 ligand, NGL-2, NLG2
UniProt ID (Human) Q9HBW1
