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Human Lefty-A quantitates human Lefty-A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Lefty-A.
Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : EBAF, LEFTA, LEFTYA, TGFB4
基因ID : (Human) 7044
基因符号 : LEFTY2
蛋白别名 : endometrial bleeding-associated factor, left-right determination factor A, MGC46222, protein lefty-2, protein lefty-A, TGF-beta-4, transforming growth factor beta-4, unnamed protein product
UniProt ID (Human) O00292