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Human MMP-7 quantitates human MMP-7 in supernatant. The assay will exclusively recognize both natural and recombinant human MMP-7.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : MMP-7, MMP7, MPSL1, PUMP-1, PUMP1
基因ID : (Human) 4316
基因符号 : MMP7
蛋白别名 : Matrilysin, Matrin, matrix metallopeptidase 7 (matrilysin, uterine), matrix metalloproteinase 7 (matrilysin, Matrix metalloproteinase-7, MMP-7, Pump-1 protease, uterine matrilysin, Uterine metalloproteinase
UniProt ID (Human) P09237