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The Human DEFB2 (Defensin Beta 2) ELISA quantitates DEFB2 in serum, plasma, and other biological fluids.
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : BD-2, DEFB-2, DEFB102, DEFB2, DEFB4, DEFB4A, DEFB4B, HBD-2, SAP1
基因ID : (Human) 1673
基因符号 : DEFB4A
蛋白别名 : BD-2, beta defensin 2, beta defensin-2, Beta-defensin 2, Defensin beta 2, Defensin beta2, Defensin-beta2, Defensin beta 4A, Defensin, beta 2, defensin, beta 4, beta 4A, SAP1, Skin-antimicrobial peptide 1
UniProt ID (Human) O15263