Search Thermo Fisher Scientific
产品规格
检测灵敏度
9.38 pg/mL
测定范围
15.63-1000 pg/mL
检测样本类型/体积
{Serum=100 µL, Plasma=100 µL}
手工操作时间
1 hr 20 min
总时间
3 hr 30 min
均相（无需洗涤）
No
批间差异
<10%
批内差异
<10%
检测仪器
Colorimetric Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer
运输条件
Wet ice
储存
Refer to product documentation for component specific storage temperature.
蛋白名称
GDNF
蛋白家族
Ligand of the TGF-beta
均相（无需洗涤）
Mouse
检测试剂盒格式
Sandwich ELISA Kit
标签或染料
HRP
关于本试剂盒
The Mouse GDNF (Glial Cell Line Derived Neurotrophic Factor) ELISA quantitates GDNF in serum, plasma, and other biological fluids
The Mouse GDNF (Glial Cell Line Derived Neurotrophic Factor) solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the binding of the second (detector) antibody to the target on a different epitope from the capture antibody. An antibody conjugated with enzyme binds the formed sandwich. After incubation and washing steps to rid the microplate of unbound substances, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation:
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
靶标信息
GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
基因别名 : AI385739, Gdnf
基因ID : (Mouse) 14573
基因符号 : Gdnf
蛋白别名 : Astrocyte-derived trophic factor, ATF, Glial cell line-derived neurotrophic factor, mGDNF, neurotrophic factor
UniProt ID (Mouse) P48540
