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Mouse IFN-alpha/beta R2 quantitates mouse IFN-alpha/beta R2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse IFN-alpha/beta R2.
The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : AI747302, Ifnar-2, Ifnar2
基因ID : (Mouse) 15976
基因符号 : Ifnar2
蛋白别名 : IFN-alpha/beta receptor 2, IFN-R-2, Interferon alpha/beta receptor 2, interferon receptor 2c, interferon-alpha/beta receptor 2, type I interferon alpha/beta receptor 2a, Type I interferon receptor 2
UniProt ID (Mouse) O35664