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Mouse PD-L1 (CD274) ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of mouse PD-L1/B7-H1 in serum, plasma, and cell culture supernatants.
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : A530045L16Rik, B7h1, Cd274, Pdcd1l1, Pdcd1lg1, Pdl1
基因ID : (Mouse) 60533
基因符号 : Cd274
蛋白别名 : B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, Programmed cell death 1 ligand 1, programmed death ligand 1, sCD274, soluble CD274, soluble PD L1, sPD L1, pdl-1
UniProt ID (Mouse) Q9EP73