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Mouse Pentraxin-3/TSG-14 quantitates mouse Pentraxin-3/TSG-14 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Pentraxin-3/TSG-14.
Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of "long pentraxins", which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : AI607804, Ptx3, TSG-14, Tsg14
基因ID : (Mouse) 19288
基因符号 : Ptx3
蛋白别名 : pentaxin related, Pentaxin-related protein PTX3, pentraxin 3, Pentraxin-related protein PTX3, TSG-14, Tumor necrosis factor-inducible gene 14 protein
UniProt ID (Mouse) P48759