Get access to posters, technical notes, white papers and webinars

Discover educational resources to support your analysis of protein structures and interactions, including articles from researchers that are actively leveraging Protein Footprinting methods.


Poster: Orbitrap Astral MS vs. Orbitrap Exploris 480 MS: Comparing the Identification of In-Cell Fast Photochemical Oxidation of Proteins Within HEK-293 and PBMCs Lisa Jones

Poster: Comparing an Epitope Identified from a Crystal Structure with In-Solution Mass Spectrometry-Based Techniques Including HRPF and XL-MS

Poster: Development of DIA workflow for Multiple Hydroxyl Radical Protein Footprinting

Poster: Improving HRPF reproducibility through end-to-end automation: Adalimumab case study comparing Manual and AccelerOme-automated digestion with and without TMT Multiplexing


For Research Use Only. Not for use in diagnostic procedures.

General Laboratory Equipment – Not For Diagnostic Procedures. © 2026 Thermo Fisher Scientific Inc. All rights reserved. Thermo Scientificproducts are designated as General Laboratory Equipment and are not intended for use in diagnostic procedures or for in vitro diagnostic purposes. These products are intended for general laboratory use only and have not been tested or validated for diagnostic applications; use for such purposes may result in inaccurate results and may pose health and safety risks. They are designed for research, academic, and industrial applications and for general-purpose analytical use, including high-resolution and accurate-mass measurements, without reference to specific clinical conditions, analytes, or diagnostic decisions.

The Thermo Scientific Orbitrap Exploris and Excedion series mass spectrometers are Orbitrap instruments with an atmospheric pressure ionization (API) source for liquid chromatography (LC) mass spectrometry (MS) high-throughput applications. The instruments are designed to be placed on a bench in the laboratory and maintain mass accuracy across chromatographic peaks, supporting confident identification and quantitation using high-resolution accurate-mass detection.