Pre-packed Chromatography Columns

Pre-packed Chromatography Columns
for Protein Purification

Save time and money by purifying your proteins using our pre-packed chromatography columns. We offer a wide range of columns pre-packed with a selection of our bioprocess chromatography resins, including affinity/capture, ion exchange or hydrophobic interaction chromatography (HIC).

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No matter what your application is, we have a packed column ready when you are. Be more productive with pre-packed columns:

Quick and easy to set up
Increased process flexibility
Allows time for more test runs
Reduced labor time related to column packing and cleaning

Pre-packed Chromatography Columns for Multiple Applications

Our pre-packed columns come in a variety of formats, suitable for high throughput screening, process development, bench-scale screening, and preparative chromatography.

Column type	Robocolumn™			GoPure™		MiniChrom™		Pre-packed
Application	High Throughput Screening Process Development			Process Development Bench-scale Screening Preparative Chromatography		Process Development Bench-scale Screening Preparative Chromatography		Pre-parative Chromatography
Volume	50 ul	200 ul	600 ul	1 ml	5ml	1 ml	5ml	1ml	5ml
Diameter	0.5 cm	0.5 cm	0.5 cm	0.5 cm	0.8 cm	0.8 cm	0.8 cm	0.7 cm	1.4 cm
Bed height	0.25 cm	1 cm	3 cm	5 cm	10 cm	2 cm	10 cm	2.5 cm	3.25 cm

High throughput screening (process development)

Robocolumns are small chromatography columns that are provided in 8-column strips. These columns are useful for fully automated and parallel chromatographic separations using a robotic liquid handling platform and are available in 50 µL, 200 µL and 600 µL volumes.

Bench-scale process development screening

The GoPure and MiniChrom columns are designed for bench-scale resin screening, process development and sample preparation. The 1 mL columns can be used for quick screenings of application feasibility and lab scale purification on a convenient and easy-to-use pre-packed column. The 10 cm bed height of the 5 mL columns allows initial process development on a bench scale.

Preparative chromatography

For your preparative chromatography needs, we have pre-packed our affinity resins into columns which can be used for simple and efficient protein purification in small volumes.

Find your column by resin type

The CaptureSelect affinity chromatography resins offer a unique affinity purification solution based on Camelid-derived single domain [VHH] antibody fragments. The affinity resins provide high target purity in a single step, independent of feedstock.

The affinity ligands are developed to meet all predefined requirements such as high specificity to the target molecule, mild elution during the purification process and high stability of the final resin. Manufacturing in an animal free production process allows for use in commercial purification processes.

Product		RoboColumn (50 µL/200 µL/600 µL)	GoPure 1mL / MiniChrom 1mL	GoPure 5mL/ MiniChrom 5mL	prepacked 1mL	prepacked 5mL
Antibodies	FcXL	5943280050 (50 µL) 5943280200 (200 µL)			494328001	494328005
	CH1-XL	5943462200 (200 µL)	5943462001	5943462005	494346201	494346205
	Kappa XL	5943210050 (50 µL) 5943210200 (200 µL)			494321001	494321005
	Kappa XP	5943212200 (200 µL)		5943212005	494321201	494321205
	MabCapture A Select	A30727 (200 µL) A30728 (600 µL)	A36646	A36645
	MabCapture A	A30725 (200 µL) A30726 (600 µL)	A36644	A36643
Proteins	HSA	5912970050 (50 µL) 5912970200 (200 µL)
Proteins	C-tagXL		5943072001	5943072005	494307201	494307205
Viral vectors	AAVX		A36652	A36651
	AAV8		A36648	A36647
	AAV9		A36650	A36649

POROS Ion Exchange Resins are designed for high-dynamic binding capacity over a range of pH and conductivity conditions, thereby increasing process development flexibility and manufacturing throughput.

POROS Anion Exchange Resins can be used in bind/elute mode to bind low PI molecules or in Flow Through mode for more basic proteins, like monoclonal antibodies, to bind impurities and flow through product. POROS HS and XS resins are strong cation exchange resins based on a sulfopropyl functionalization, designed for the purification of more basic proteins and biomolecules. They are especially well suited for the separation of process impurities and aggregates.

Resin Type	Product	RoboColumn 200 µL	RoboColumn 600 µL	GoPure 1 mL	GoPure 5mL
Anion	HQ 50	A30717	A30718	4481315	A36639
	XQ	A30719	A30720	A25812	A36640
	PI 50	A30721	A30722	4481318	A36641
	D 50	A30723	A30724	4481319	A36642
Cation	HS 50	A30713	A30714	4481316	A36637
Cation	XS	A30715	A30716	4481317	A36638

POROS HIC resins are available in a differentiating range of hydrophobicity, suitable for bind/elute and flow-through applications. The resins can be utilized at lower salt concentrations for the purification of a wide variety of biomolecules including therapeutic proteins, antibody fragments, antibody drug conjugates (ADCs), and other large molecules.

Resin Type	Product	RoboColumn 200 µL	RoboColumn 600 µL	GoPure 1mL	GoPure 5mL
HIC	Ethyl	A34810	A34812	A34983	A36653
	Benzyl	A34813	A34814	A34984	A36654
	Benzyl Ultra	A34815	A34816	A34985	A36655

Affinity

Product		RoboColumn (50 µL/200 µL/600 µL)	GoPure 1mL / MiniChrom 1mL	GoPure 5mL/ MiniChrom 5mL	prepacked 1mL	prepacked 5mL
Antibodies	FcXL	5943280050 (50 µL) 5943280200 (200 µL)			494328001	494328005
	CH1-XL	5943462200 (200 µL)	5943462001	5943462005	494346201	494346205
	Kappa XL	5943210050 (50 µL) 5943210200 (200 µL)			494321001	494321005
	Kappa XP	5943212200 (200 µL)		5943212005	494321201	494321205
	MabCapture A Select	A30727 (200 µL) A30728 (600 µL)	A36646	A36645
	MabCapture A	A30725 (200 µL) A30726 (600 µL)	A36644	A36643
Proteins	HSA	5912970050 (50 µL) 5912970200 (200 µL)
Proteins	C-tagXL		5943072001	5943072005	494307201	494307205
Viral vectors	AAVX		A36652	A36651
	AAV8		A36648	A36647
	AAV9		A36650	A36649

Ion Exchange

Resin Type	Product	RoboColumn 200 µL	RoboColumn 600 µL	GoPure 1 mL	GoPure 5mL
Anion	HQ 50	A30717	A30718	4481315	A36639
	XQ	A30719	A30720	A25812	A36640
	PI 50	A30721	A30722	4481318	A36641
	D 50	A30723	A30724	4481319	A36642
Cation	HS 50	A30713	A30714	4481316	A36637
Cation	XS	A30715	A30716	4481317	A36638

Hydrophobic Interaction

Resin Type	Product	RoboColumn 200 µL	RoboColumn 600 µL	GoPure 1mL	GoPure 5mL
HIC	Ethyl	A34810	A34812	A34983	A36653
	Benzyl	A34813	A34814	A34984	A36654
	Benzyl Ultra	A34815	A34816	A34985	A36655

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