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Invitrogen
Human C19orf48 Control Fragment Recombinant Protein
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产品信息
RP-99147
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPR
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (40%), Rat (40%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59814. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The C19orf48 gene, located on chromosome 19q13, encodes a protein involved in various biological processes, including its role as a minor histocompatibility antigen recognized by CD8+ T cells. This gene has been implicated in oncogenesis due to its elevated expression in certain cancer types, such as breast cancer, where it has been associated with poor prognosis. The non-synonymous single-nucleotide polymorphisms within C19orf48 contribute to differential T-cell recognition in donor and recipient cells, highlighting its significance in immune responses. Additionally, C19orf48 has been linked with SNORD88C, a small nucleolar RNA (snoRNA) that guides methylation of rRNA, further illustrating its involvement in cellular proliferation and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: multidrug resistance-related protein
Entrez Gene ID: (Human) 84798
