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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82943. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-glucosidase 2; Glucosidase II subunit alpha; Neutral alpha-glucosidase AB
基因别名: G2AN; GANAB; GIIA; GLUII; KIAA0088
UniProt ID: (Human) Q14697
Entrez Gene ID: (Human) 23193