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产品信息
PEP-1398
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Dry ice
产品详细信息
This peptide corresponds to 19 amino acids near the amino terminus of human HHATL.
PEP-1398 can be used as a blocking peptide with polyclonal antibody PA5-34355.
靶标信息
The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glycerol uptake/transporter homolog; GUP1 glycerol uptake/transporter homolog; Hedgehog acyltransferase-like protein; membrane bound O-acyltransferase domain containing 3; Protein-cysteine N-palmitoyltransferase HHAT-like protein
基因别名: C3orf3; GUP1; HHATL; KIAA1173; MBOAT3; MSTP002; OACT3
UniProt ID: (Human) Q9ULP7
Entrez Gene ID: (Human) 57467
