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产品信息
PV3300
产品规格
种属
Human
Expression System
Insect cells
氨基酸序列
Full length
标签
His-tag
分子量
47.3 kDa
分类
Recombinant
类型
Protein
纯度
95% by SDS-PAGE
偶联物
Unconjugated
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris, pH 7.5, with 0.05mM EDTA, 50% glycerol, 2mM DTT, 150mM NaCl, 0.05% Triton X-100
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Protein Form: Full Length, Recombinant, Inactive
靶标信息
MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. MAPKAPK3 was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3pK; Chromosome 3p kinase; MAP kinase-activated protein kinase 3; MAPK-activated protein kinase 3; MAPKAP kinase 3; OTTHUMP00000210806; OTTHUMP00000210807
基因别名: 3PK; MAPKAP-K3; MAPKAP3; MAPKAPK-3; MAPKAPK3; MK-3
UniProt ID: (Human) Q16644
Entrez Gene ID: (Human) 7867
