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Invitrogen
Human MCT2 (aa 199-240) Control Fragment Recombinant Protein
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产品信息
RP-88754
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
GPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (48%), Rat (48%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52225. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MCT 2; monocarboxylate transporter; Monocarboxylate transporter 2; solute carrier family 16 (monocarboxylate transporter), member 7; Solute carrier family 16 member 7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
基因别名: MCT2; SLC16A7
UniProt ID: (Human) O60669
Entrez Gene ID: (Human) 9194
