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Invitrogen
Human MMP27 (aa 321-386) Control Fragment Recombinant Protein
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产品信息
RP-104100
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
FWPSLPADLQAAYENPRDKILVFKDENFWMIRGYAVLPDYPKSIHTLGFPGRVKKIDAAVCDKTTR
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64398. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: matrix metallo protease; matrix metalloprotease 27; matrix metalloproteinase 27; Matrix metalloproteinase-27; MMP; MMP-27; MMPs
基因别名: MMP-27; MMP27; UNQ2503/PRO5992
UniProt ID: (Human) Q9H306
Entrez Gene ID: (Human) 64066
