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产品信息
PV3690
产品规格
种属
Human
Expression System
Insect cells
氨基酸序列
Full length
标签
GST-tag
分子量
75.7 kDa
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris, pH 7.5, with 0.02% Triton X-100, 50% glycerol, 150mM NaCl, 2mM DTT, 0.5mM EDTA
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Protein Form: Full Length
靶标信息
MST4 is member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Mammalian STE20-like protein kinase 4; mammalian sterile 20-like 4; MST-4; MST3 and SOK1-related kinase; OTTHUMP00000215132; OTTHUMP00000215134; RP6-213H19.1; serine/threonine protein kinase MST4; Serine/threonine-protein kinase 26; Serine/threonine-protein kinase MASK; STE20-like kinase 4; STE20-like kinase MST4
基因别名: MASK; MST4; STK26
UniProt ID: (Human) Q9P289
Entrez Gene ID: (Human) 51765
