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Invitrogen
Human PPAN (aa 421-460) Control Fragment Recombinant Protein
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产品信息
RP-99100
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
RWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGG
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (38%), Rat (38%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60302. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brix domain-containing protein 3; homolog of S. cerevisiae SSF1; Peter Pan homolog; second-step splicing factor 1; Ssf-1; suppressor of sterile four 1; Suppressor of SWI4 1 homolog
基因别名: BXDC3; PPAN; SSF; SSF-1; SSF1; SSF2
UniProt ID: (Human) Q9NQ55
Entrez Gene ID: (Human) 56342
