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Invitrogen
Human PPAPDC3 (aa 170-202) Control Fragment Recombinant Protein
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产品信息
RP-107737
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
GPYETSPSLLDYLTMDIYAFPAGHASRAAMVSK
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67093. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Inactive phospholipid phosphatase 7; nuclear envelope transmembrane protein NET39; phosphatidic acid phosphatase type 2 domain containing 3; Phosphatidic acid phosphatase type 2 domain-containing protein 3; probable lipid phosphate phosphatase PPAPDC3; RP11-643E14.1
基因别名: C9orf67; NET39; PLPP7; PPAPDC3
UniProt ID: (Human) Q8NBV4
Entrez Gene ID: (Human) 84814
