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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66741. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: protein G16; ram1 homolog; ring finger protein 5, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase RNF5; unnamed protein product
基因别名: RING5; RMA1
UniProt ID: (Human) Q99942
Entrez Gene ID: (Human) 6048