This peptide corresponds to 13 amino acids near the amino terminus of human Raptor.
PEP-0243 can be used as a blocking peptide with polyclonal antibody PA5-20125.
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
蛋白别名: p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Raptor; regulatory associated protein of MTOR, complex 1; Regulatory-associated protein of mTOR
基因别名: KIAA1303; KOG1; Mip1; RAPTOR; RPTOR
UniProt ID: (Human) Q8N122
Entrez Gene ID: (Human) 57521