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Invitrogen
Human THRA, Ligand Binding Domain, GST Tag Recombinant Protein
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产品信息
PV4762
产品规格
种属
Human
Expression System
Baculovirus
氨基酸序列
148-410
标签
GST-tag
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
proprietary buffer
内含物
no preservative
保存条件
-80°C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
Thyroid Receptor alpha, Ligand Binding Domain (THRA LBD ) is a 57.90 kDa recombinant human protein (amino acids 148-410) expressed as a GST-tagged fusion protein in baculovirus-infected insect cells. THRA LBD was expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.
Protein Form: Recombinant, Ligand Binding Domain
靶标信息
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: c-erbA protooncogene; c-erbA-1; c-erbA-alpha; cerbA protein; cerbAalpha; E ERB-T-1; EAR-7; ERBA ALPHA; ERBA related 7; ERBA-related 7; MGC000261; MGC43240; Nuclear receptor subfamily 1 group A member 1; Oncogene ERBA; THRA; Thyroid hormone receptor alpha; thyroid hormone receptor alpha 1; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); TR; TR alpha 1+2; triiodothyronine receptor; unnamed protein product; V-erbA-related protein 7
基因别名: AR7; c-erbA; c-ERBA-1; CHNG6; EAR7; ERB-T-1; ERBA; ERBA1; NR1A1; THRA; THRA1; THRA2; THRalpha; THRalpha1; THRalpha2; TRalpha; TRalpha1; TRalpha2
UniProt ID: (Human) P10827
Entrez Gene ID: (Human) 7067
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