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Gibco
PeproGMP® Human IL-7 Recombinant Protein, PeproTech®
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PeproGMP® Human IL-7 Protein (GMP200-07-50UG) in Bioactivity
Bioassay of PeproGMP® Human IL-7 Recombinant Protein, PeproTech (Product # GMP200-07-50UG) compared to Human IL-7, Animal-Free Recombinant Protein, PeproTech (Product # AF-200-07-01M) and Human IL-7 Recombinant Protein, PeproTech (Product # 200-07-01M), demonstrating comparable bioactivity across product grades.
产品信息
GMP200-07-50UG
应用
建议稀释比
已发表文章
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
DCDIEGKDGK QYESVLMVSI DQLLDSMKEI GSNCLNNEFN FFKRHICDAN KEGMFLFRAA RKLRQFLKMN STGDFDLHLL KVSEGTTILL NCTGQVKGRK PAALGEAQPT KSLEENKSLK EQKKLNDLCF LKRLLQEIKT CWNKILMGTK EH
分子量
17.4 kDa
分类
Recombinant
类型
Protein
纯度
≥ 98% by SDS-PAGE gel and HPLC analyses.
内毒素浓度
≤0.1 EU/µg
活性
Determined by the proliferation of mouse 2E8 cells. PeproGMP Recombinant Human IL-7 has been tested against the WHO standard NIBSC 90/530. Find the International Unit (IU) value here.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient
产品详细信息
PeproTech Recombinant Human IL-7 is a 17.4 kDa protein containing 152 amino acid residues.
PeproGMP IL-7 can be used with PeproGMP IL-15 in CTS NK-Xpander medium for natural killer (NK) cell differentiation from pluripotent stem cells.
Reconstitute using sterile water (i.e., WFI) to a concentration of 0.1-1.0 mg/ml.
Additional product information, specifications, handling and reconstitution information are provided on the Certificate of Analysis.
All PeproGMP® products are manufactured using animal-derived component free materials.
Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter <1043> Ancillary Materials for Cell, Gene, and Tissue-Engineered Products.
靶标信息
Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and natural killer cells.
For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.
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生物信息学
蛋白别名: CD127; CD127 antigen; CDw127; H-IL-7; IL-7; IL-7 receptor subunit alpha; IL-7R subunit alpha; ILN; Interleukin; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin-7; Interleukin-7 receptor subunit alpha; Interleukin7; M-IL-7
基因别名: CD127; CDW127; IL-7; IL-7R-alpha; IL7; IL7R; IL7RA; ILRA
UniProt ID: (Human) A0N0L3, (Human) P16871
Entrez Gene ID: (Human) 3574, (Human) 3575
