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Canine Decorin quantitates canine Decorin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine Decorin.
Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CSCD, DCN, DCN1C, DSPG2, PG40, PGII, PGS2, SLRR1B
基因ID : (Human) 1634, (Dog) 403904
基因符号 : DCN, DCN
蛋白别名 : Bone proteoglycan II, Decorin, dermatan sulphate proteoglycans II, Dermatan sulphate proteoglycans II (DSPG2), Small leucine rich protein 1B, PG-S2, PG40, proteoglycan core protein, small leucine-rich protein 1B
UniProt ID (Human) P07585, (Dog) Q29393