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Invitrogen
Human 4-1BB Ligand ELISA Kit
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产品规格
检测灵敏度
0.2 ng/mL
测定范围
0.2-50 ng/mL
检测样本类型/体积
{Serum=50 µL, Plasma=50 µL, Supernatant=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
4-1BBL (CD137L)
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human 4-1BB Ligand quantitates human 4-1BB Ligand in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human 4-1BB Ligand.
靶标信息
CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily. CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation. Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes. Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity. CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma (but it is lacking on Hodgkin lymphoma and T-cell lymphoma). CD137L is also expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interactions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : 4-1BB-L, CD137L, TNFSF9, TNLG5A
基因ID : (Human) 8744
基因符号 : TNFSF9
蛋白别名 : 4 1 BB Ligand, 4 1 BBL, 41BB Ligand, 41BBL, CD 137 Ligand, CD 137L, CD137 Ligand, CDw137L, TNFRSF9, 4-1BB ligand, 4-1BBL, CD137 ligand, homolog of mouse 4-1BB-L, receptor 4-1BB ligand, tumor necrosis factor (ligand) superfamily, member 9, tumor necrosis factor ligand 5A, Tumor necrosis factor ligand superfamily member 9, tumor necrosis factor superfamily member 9, unnamed protein product
UniProt ID (Human) P41273
