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900-K149K consists of: 900-K149 (capture antibody, detection antibody, and protein standard), and AVIDIN-60UL (avidin HRP-conjugate).
Human TWEAK ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant human TWEAK in a sandwich ELISA format. Human TWEAK ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.
The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : APO3L, DR3LG, TNFSF12, TNLG4A, TWEAK, UNQ181/PRO207
基因ID : (Human) 8742
基因符号 : TNFSF12
蛋白别名 : APO3 ligand, APO3/DR3 ligand, MGC129581, MGC20669, TNF-related WEAK inducer of apoptosis, tumor necrosis factor (ligand) superfamily member 12, tumor necrosis factor (ligand) superfamily, member 12, tumor necrosis factor ligand 4A, Tumor necrosis factor ligand superfamily member 12, TWEAK
UniProt ID (Human) O43508