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Invitrogen
Mouse 4-1BB Ligand ELISA Kit
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产品规格
检测灵敏度
0.75 ng/mL
测定范围
0.75-200 ng/mL
检测样本类型/体积
{Serum=100 µL, Plasma=100 µL, Supernatant=100 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
12%
批内差异
10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated microwell plate
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Sample Diluent
Wash Buffer Concentrate
Assay Buffer concentrate
Stop Solution
Substrate Solution
Adhesive Plate Covers
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Sample Diluent
Wash Buffer Concentrate
Assay Buffer concentrate
Stop Solution
Substrate Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
-20°C
蛋白名称
4-1BBL (CD137L)
均相（无需洗涤）
Mouse
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Mouse 4-1BB Ligand ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of mouse 4-1BB Ligand (TNFSF9) in serum, plasma, and cell culture supernatants.
靶标信息
CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily. CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation. Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes. Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity. CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma (but it is lacking on Hodgkin lymphoma and T-cell lymphoma). CD137L is also expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interactions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : 4-1BB-L, 4-1BBL, AI848817, Cd137l, Cd157l, Ly63l, Tnfsf9
基因ID : (Mouse) 21950
基因符号 : Tnfsf9
蛋白别名 : 4 1 BB Ligand, 4 1 BBL, 41BB Ligand, 41BBL, CD 137 Ligand, CD 137L, CD137 Ligand, CDw137L, TNFRSF9, 4-1BB ligand, 4-1BBL, Tumor necrosis factor ligand superfamily member 9
UniProt ID (Mouse) P41274
