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The Mouse Connective Tissue Growth Factor (CTGF) ELISA quantitates CTGF in serum, plasma, and other biological fluids
The Mouse Connective Tissue Growth Factor (CTGF) solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the binding of the second (detector) antibody to the target on a different epitope from the capture antibody. An antibody conjugated with enzyme binds the formed sandwich. After incubation and washing steps to rid the microplate of unbound substances, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation:
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : betaIG-M2, Ccn2, Ctgf, Fisp-12, Fisp12, Hcs24
基因ID : (Mouse) 14219
基因符号 : Ctgf
蛋白别名 : 2-Nov, H-CTGF, MGC102839, CCN family member 2, Cellular communication network factor 2, Connective tissue growth factor, Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24), fibroblast inducible secreated protein, fibroblast inducible secreted protein, hypertrophic chondrocyte-specific gene product 24, Hypertrophic chondrocyte-specific protein 24, Protein FISP-12
UniProt ID (Mouse) P29268