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The Mouse Serum Amyloid A (Ms SAA) ELISA quantitates Ms SAA in mouse serum and plasma. The assay will exclusively recognize both natural and recombinant Ms SAA.
原理方法
The Mouse SAA solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; SAA rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : Saa-1, Saa1, Saa2
基因ID : (Mouse) 20208
基因符号 : Saa1
蛋白别名 : amyloid a, MGC111216, Serum amyloid A1 protein, Serum Amyloid-A, serum amyloid A 2, Serum amyloid A-1 protein
UniProt ID (Mouse) P05366