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Invitrogen
Rat Growth Hormone R ELISA Kit
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产品规格
检测灵敏度
0.14 ng/mL
测定范围
0.14-100 ng/mL
检测样本类型/体积
{Supernatant=50 µL, Plasma=50 µL, Serum=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
Growth Hormone Receptor
均相（无需洗涤）
Rat
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Rat Growth Hormone R quantitates rat Growth Hormone R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat Growth Hormone R.
靶标信息
Growth hormone receptor (GHR) is a gene located on chromosome 5p13.1, encoding a transmembrane receptor that plays a critical role in mediating the effects of growth hormone, which is crucial for growth, metabolism, and tissue development. GHR is expressed in various tissues, including the liver, muscle, and adipose tissue, and facilitates the growth hormone signaling pathway by binding to growth hormone, leading to receptor dimerization and activation of intracellular signaling cascades such as the JAK2-STAT5 pathway. This signaling promotes growth and anabolic processes, influencing body composition, insulin sensitivity, and lipid metabolism. Mutations or alterations in the GHR gene can lead to growth disorders like Laron syndrome, characterized by insensitivity to growth hormone. Understanding GHR's structure and function is pivotal for developing therapeutic strategies for growth deficiencies and metabolic syndromes, as modifying GHR signaling pathways can offer potential interventions in related conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : Ghr, GHR/BP
基因ID : (Rat) 25235
基因符号 : Ghr
蛋白别名 : GH receptor, Growth hormone receptor, growth hormone receptor precursor splice variant D56, growth hormone receptor variant d5-6, growth hormone receptor/binding protein, MGC124963, MGC156665, Somatotropin receptor
UniProt ID (Rat) P16310
