Dish QC (DQC) is the recommended QC metric for Axiom Genome-Wide Arrays in Genotyping Console Software. The default threshold is greater than or equal to 0.82 for each sample. It operates by measuring signal at a collection of sites in the genome that are known not to vary from one individual to the next. Because the metric monitors non-polymorphic locations, at each position it is known which of the two channels in the assay should contain signal and which should be just background. DQC is a measure of the extent to which the distribution of signal values is separated from background values, with 0 indicating no separation and 1 indicating perfect separation.
Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.