The dynamics and mechanics of endothelial cell spreading.
AuthorsReinhart-King CA, Dembo M, Hammer DA
JournalBiophys J
PubMed ID15849250
Cell adhesion to extracellular matrix is mediated by receptor-ligand interactions. When a cell first contacts a surface, it spreads, exerting traction forces against the surface and forming new bonds as its contact area expands. Here, we examined the changes in shape, actin polymerization, focal adhesion formation, and traction stress generation ... More