We tested the paper cooler side-by-side with our current expanded polystyrene coolers with three gel packs in simulated summer and winter shipping conditions using the ISTA 7E profiles, the industry standard profiles for laboratory and medical products. We have also tested the cooler’s performance under real-world shipment conditions in our global intercompany distribution network. The performance of the paper cooler is similar or better when compared to the performance of our expanded polystyrene coolers. Note that the number of ice packs used with the paper cooler may vary based on anticipated package transit times and seasonal temperature variations. The paper cooler has also been internally tested and validated for cold shipments requiring dry ice coolant.