Gibco™

人 OAT3 (G) SLC 转运细胞

货号: GM1104G
Gibco™

人 OAT3 (G) SLC 转运细胞

货号: GM1104G
货号
GM1104G
单位规格
8–10M cells
价格(CNY)
货号单位规格价格(CNY)
GM1104G8–10M cells联系我们 ›
产品概述
图表
视频
推荐产品
推荐产品
文件
常见问题解答
引用和文献
其他信息
推荐产品
TRANSiPORT Human OAT3 (G) SLC Transporter Cells are HEK293 cells that transiently overexpress the OAT3 solute carrier (SLC) transport protein. Solute carriers are a super-family of membrane transporters that can affect pharmacokinetics and drug exposure by governing the transport of solutes in and out of cells. The OAT3 SLC transporter protein is found in kidney proximal tubule, choroid plexus, and brain endothelial cells.

• Assess potential for transporter-mediated drug metabolism
• Easy to use format
• Obtain high quality results with a large signal-to-noise ratio

Choice of measurement system
Cell-based assays can be performed using radioisotope-labeled compounds, fluorescence-labeled compounds, or non-labeled compounds. The amount of substrate transported into the cells can be measured directly using a liquid scintillation counter, fluorescence plate reader, or LC-MS/MS, thereby allowing direct evaluation of SLC transporter activity.

Assay reliability
Mock HEK293 cells (Cat. No. GM1101G) that do not overexpress the SLC transporter are available for use as a negative experimental control. Some compounds may demonstrate high background levels of transport due to the presence of endogenous transporters or non-specific binding.

Rapid results
The convenient product format enables data generation in 2 days from thawing of the cells to final results.

Related products
GM1102G Human OATP1B1 (G) SLC Transporter Cells
GM1103G Human OAT1 (G) SLC Transporter Cells
GM1105G Human OCT2 (G) SLC Transporter Cells
GM1106G Human OATP1B3 (G) SLC Transporter Cells
GM1108G Human OCT1 (G) SLC Transporter Cells
GM1113G Human NTCP (G) SLC Transporter Cells
GM1114G Human MATE1 (G) SLC Transporter Cells
GM1115G Human MATE2K (G) SLC Transporter Cells
GM1101G Mock Cells

规格

细胞系
293 (HEK)
Culture Type
哺乳动物细胞培养
种属
产品类型
SLC 转运体细胞
数量
8 至 10M 个细胞

内容与储存

储存于液氮(汽相)中。

图表

文件和下载

证书

    常见问题解答 (FAQ)

    引用和文献

    Search citations by name, author, journal title or abstract text