可铺板培养人肝细胞，摄取测试合格
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可铺板培养人肝细胞，摄取测试合格
Gibco™

可铺板培养人肝细胞，摄取测试合格

冻存人肝细胞，用于转运体介导的摄取应用。细胞/样品瓶：400-800 万分别用典型肝摄取性转运体底物牛磺胆酸盐和雌二醇-17β-葡萄糖苷酸评估了肝 NTCP (SLC10A1) 和 OATP1B14/3 (SLCO1B1/3) 的转运功能。通过闪烁分析监测各底物了解更多信息
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货号数量
HMCPUS1.5 mL
货号 HMCPUS
价格（CNY)
23,644.00
Each
添加至购物车
数量:
1.5 mL
价格（CNY)
23,644.00
Each
添加至购物车
冻存人肝细胞，用于转运体介导的摄取应用。

细胞/样品瓶：400-800 万

分别用典型肝摄取性转运体底物牛磺胆酸盐和雌二醇-17β-葡萄糖苷酸评估了肝 NTCP (SLC10A1) 和 OATP1B14/3 (SLCO1B1/3) 的转运功能。通过闪烁分析监测各底物（放射性标记）的转运，通过线性回归确定主动转运值 (37°C - 4°C)。

使用 GIBCO™ 肝细胞获得您需要的结果
高质量的肝细胞，具有高存活率、与体内相似的酶表达水平和适当的细胞形态学，这都增强了判定体外/体内相关性的能力，并就化合物的结局做出合理的判定。经验丰富的技术人员、已获专利的分离技术、再辅以严格的放行标准，确保您获得最高品质的冻存肝细胞。

每批细胞均进行了以下测试：


• I 相和 II 相酶活性
• 正常形态
• 存活率通常 >75%
• 贴壁率
• 单层形成能力和完整性

仅供研究使用。不适用于人或动物治疗或诊断用途。

相关链接

请参阅了解更多关于我们的冻存肝细胞的信息

请参阅了解我们的全系列肝细胞的信息
仅供科研使用。不可用于诊断程序。
规格
细胞传代次数传代 0
供体单一供体
产品规格管装
池数量4-8 x 10^6
产品线Gibco™
产品类型肝细胞
数量1.5 mL
细胞类型肝细胞
培养类型贴壁细胞培养
形式冻存
种属人
Unit SizeEach
内容与储存
管装冻存肝细胞应储存在低温储存杜瓦瓶或 -135°C 冷冻冰箱中。

常见问题解答 (FAQ)

Who should I contact if I am looking for hepatocytes with particular characteristics?

Our hepatocytes are prequalified and sold according to application, such as induction, short-term metabolism, and transporter uptake. If you require hepatocytes with particular P450 values or donor specifications, contact our Hepatic Biology Tech Support Team (hepaticproducts@thermofisher.com.com) or (866) 952-3559 to help with specific lot recommendations.

Who can I call if I have technical questions about hepatocyte cell culture?

Thermo Fisher Scientific has a dedicated team to answer questions regarding hepatocyte cell culture. You can send a question by email (hepaticproducts@thermofisher.com) or contact us by phone: US toll-free: (866) 952-3559

Are there guidelines for the procurement of human liver tissue?

Thermofisher Scientific works with a variety of human tissue sources, including Tissue and Organ Procurement Organizations, qualified Research Tissue Organizations and prominent academic and medical centers through collaborations that follow rigorous regulations, certifications and/or accreditations (“Source Facilities”). Tissues obtained through source facilities are consistent with the applicable legal and ethical practices of the United States.

Source Facilities are required by federal law to maintain accurate records and donor confidentiality as well as adhere to certain applicable laws governing tissue used for research globally. These include, but are not limited to:

- 45 CFR Part 46, subparts A, B, C, D where applicable (US federal guidance on the use of human subjects in research)
- Health Insurance Portability and Accountability Act (HIPAA) (addressing issues of confidentiality of personal information)
- National Organ Transplant Act (42 CFR Part 482)
- The Uniform Anatomical Gift Act (UAGA) of 1968, revised 1984

Where do you get your human liver tissue?

The human liver cells are derived from tissue obtained from accredited institutions. Consent is obtained by these institutions from the donor or the donor’s legal next of kin, for the use of the tissue and its derivatives for research purpose.

What should I plate hepatocyte cells on?

Hepatocytes need to be plated on collagen I-coated culture vessels.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

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