Invitrogen™

MitoSOX™ Mitochondrial Superoxide Indicators, for live-cell imaging

货号: M36008
Invitrogen™

MitoSOX™ Mitochondrial Superoxide Indicators, for live-cell imaging

货号: M36008
MitoSOX Green and MitoSOX Red superoxide indicators are novel fluorogenic dyes specifically targeted to mitochondria in live cells. Oxidation of the MitoSOX reagent by mitochondrial superoxide produces bright green or red fluorescence.
 
货号
M36008
单位规格
10 x 50 µg
Indicator
MitoSox Red
颜色
Red
Excitation/Emission
396/610 nm
数量
10 Vials
价格(CNY)
价格 4,896.00
飞享价 3,672.00
(结束31-Dec-2022)
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库存状况
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完整规格
数量
颜色Red
检测方法Fluorescence
Excitation/Emission396/610 nm
IndicatorMitoSox Red
产品线MitoSOX™
产品规格Vial(s)
数量10 Vials
Unit Size10 x 50 µg
货号
单位规格
9 µg
Indicator
MitoSox Green
颜色
Green
Excitation/Emission
488/510 nm
数量
1 Vial
价格(CNY)
价格 1,836.00
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完整规格
数量
颜色Green
检测方法Fluorescence
Excitation/Emission488/510 nm
IndicatorMitoSox Green
产品线MitoSOX™
数量1 Vial
Unit Size9 µg
货号
单位规格
5 x 9 µg
Indicator
MitoSox Green
颜色
Green
Excitation/Emission
488/510 nm
数量
5 Vials
价格(CNY)
价格 4,788.00
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库存状况
***
完整规格
数量
颜色Green
检测方法Fluorescence
Excitation/Emission488/510 nm
IndicatorMitoSox Green
产品线MitoSOX™
数量5 Vials
Unit Size5 x 9 µg
货号
单位规格
50 µg
Indicator
MitoSox Red
颜色
Red
Excitation/Emission
396/610 nm
数量
1 Vial
价格(CNY)
价格 1,836.00
您的价格
库存状况
***
完整规格
数量
颜色Red
检测方法Fluorescence
Excitation/Emission396/610 nm
IndicatorMitoSox Red
产品线MitoSOX™
数量1 Vial
Unit Size50 µg
货号
单位规格
2 vials
Indicator
MitoSox Green & MitoSox Red
颜色
Green, Red
Excitation/Emission
488/510 nm (green), 396/610 nm (red)
数量
2 Vials (1 Green, 1 Red)
价格(CNY)
价格 3,000.00
您的价格
库存状况
***
完整规格
数量
颜色Green, Red
检测方法Fluorescence
Excitation/Emission488/510 nm (green), 396/610 nm (red)
IndicatorMitoSox Green & MitoSox Red
产品线MitoSOX™
数量2 Vials (1 Green, 1 Red)
Unit Size2 vials
显示5,共5
货号规格单位规格Indicator颜色Excitation/Emission数量价格(CNY)库存状况数量
M36008完整规格
10 x 50 µgMitoSox RedRed396/610 nm10 Vials
价格 4,896.00
飞享价 3,672.00
(结束31-Dec-2022)
您的价格
***
颜色Red
检测方法Fluorescence
Excitation/Emission396/610 nm
IndicatorMitoSox Red
产品线MitoSOX™
产品规格Vial(s)
数量10 Vials
Unit Size10 x 50 µg
M36005完整规格
9 µgMitoSox GreenGreen488/510 nm1 Vial
价格 1,836.00
您的价格
***
颜色Green
检测方法Fluorescence
Excitation/Emission488/510 nm
IndicatorMitoSox Green
产品线MitoSOX™
数量1 Vial
Unit Size9 µg
M36006完整规格
5 x 9 µgMitoSox GreenGreen488/510 nm5 Vials
价格 4,788.00
您的价格
***
颜色Green
检测方法Fluorescence
Excitation/Emission488/510 nm
IndicatorMitoSox Green
产品线MitoSOX™
数量5 Vials
Unit Size5 x 9 µg
M36007完整规格
50 µgMitoSox RedRed396/610 nm1 Vial
价格 1,836.00
您的价格
***
颜色Red
检测方法Fluorescence
Excitation/Emission396/610 nm
IndicatorMitoSox Red
产品线MitoSOX™
数量1 Vial
Unit Size50 µg
M36009完整规格
2 vialsMitoSox Green & MitoSox RedGreen, Red488/510 nm (green), 396/610 nm (red)2 Vials (1 Green, 1 Red)
价格 3,000.00
您的价格
***
颜色Green, Red
检测方法Fluorescence
Excitation/Emission488/510 nm (green), 396/610 nm (red)
IndicatorMitoSox Green & MitoSox Red
产品线MitoSOX™
数量2 Vials (1 Green, 1 Red)
Unit Size2 vials
显示5,共5
Features of these indicators include:
• Readily oxidized by superoxide but not by other ROS- or RNS-generating systems
• Use for live cell imaging
• Rapidly and selectively targeted to the mitochondria
• MitoSOX Green indicator: absorption/emission maxima of ∼488/510 nm (traditional FITC/GFP filter set)
• MitoSox Red indicator: absorption/emission maxima of ∼396/610 nm* (custom filter set recommended)

*Robinson et al. (1) reported that if MitoSOX Red dye is excited at 396 nm instead of 510 nm, it can be a more selective marker for mitochondrial superoxide.

MitoSOX Green indicator is offered as one vial or a pack of five vials. MitoSOX Red indicator is offered as one vial or a pack of ten vials. A variety pack of one vial each of MitoSOX Red and MitSOX Green indicators is also available.

Quick, easy detection of mitochondrial superoxide in live cells
The production of superoxide by mitochondria can be visualized in fluorescence microscopy using MitoSOX superoxide indicators. They permeate live cells where they selectively target mitochondria. They are rapidly oxidized by superoxide but not by other reactive oxygen species (ROS) and reactive nitrogen species (RNS). The oxidized product is highly fluorescent.

MitoSOX indicators may be used to distinguish artifacts of isolated mitochondrial preparations from direct measurements of superoxide generated in the mitochondria of live cells. They may also provide a valuable tool in the research of agents that modulate oxidative stress in various pathologies. In addition, these indicators have been used in metabolic flux assays using high-content instruments (2). MitoSOX indicators have also been used to detect mitochondrial superoxide using flow cytometery (3).

References
1: Robinson, Kristine M., et al. Selective fluorescent imaging of superoxide in vivo using ethidium-based probes. Proceedings of the National Academy of Sciences 103.41 (2006): 15038-15043.
2: Little, Andrew Charles, et al. High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions. Communications biology 3.1 (2020): 1-10.
3: Kauffman, Megan E. et al. MitoSOX-Based Flow Cytometry for Detecting Mitochondrial ROS. Reactive oxygen species (Apex, N.C.) vol. 2,5 (2016): 361-370.

For Research Use Only. Not for use in diagnostic procedures.

内容与储存

在冷冻冰箱(-5 至 -30°C)中避光储存。