TNF alpha Monoclonal Antibody (E10041)

protease binding identical protein binding cytokine activity tumor necrosis factor receptor binding protein binding transcription regulatory region DNA binding

negative regulation of transcription from RNA polymerase II promoter activation of MAPKKK activity activation of MAPK activity microglial cell activation negative regulation of endothelial cell proliferation chronic inflammatory response to antigenic stimulus positive regulation of chronic inflammatory response to antigenic stimulus positive regulation of humoral immune response mediated by circulating immunoglobulin glucose metabolic process activation of cysteine-type endopeptidase activity involved in apoptotic process humoral immune response JNK cascade intrinsic apoptotic signaling pathway in response to DNA damage response to virus vascular endothelial growth factor production negative regulation of alkaline phosphatase activity extracellular matrix organization osteoclast differentiation sequestering of triglyceride cortical actin cytoskeleton organization positive regulation of fever generation lipopolysaccharide-mediated signaling pathway negative regulation of interleukin-6 production positive regulation of interferon-gamma production positive regulation of interleukin-6 production positive regulation of interleukin-8 production receptor biosynthetic process positive regulation of peptidyl-serine phosphorylation positive regulation of heterotypic cell-cell adhesion negative regulation of myosin-light-chain-phosphatase activity negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of protein complex disassembly positive regulation of protein complex disassembly protein kinase B signaling positive regulation of JUN kinase activity positive regulation of neuron apoptotic process negative regulation of viral genome replication positive regulation of chemokine biosynthetic process positive regulation of nitric oxide biosynthetic process regulation of fat cell differentiation negative regulation of myoblast differentiation negative regulation of osteoblast differentiation positive regulation of osteoclast differentiation negative regulation of mitotic cell cycle positive regulation of translational initiation by iron negative regulation of glucose import embryonic digestive tract development positive regulation of cytokine secretion positive regulation of phagocytosis regulation of insulin secretion positive regulation of synaptic transmission regulation of synapse organization defense response to Gram-positive bacterium leukocyte tethering or rolling negative regulation of lipid catabolic process regulation of immunoglobulin secretion positive regulation of membrane protein ectodomain proteolysis positive regulation of NF-kappaB transcription factor activity response to glucocorticoid positive regulation of hair follicle development positive regulation of protein kinase B signaling positive regulation of glial cell proliferation positive regulation of calcidiol 1-monooxygenase activity epithelial cell proliferation involved in salivary gland morphogenesis regulation of branching involved in salivary gland morphogenesis negative regulation of branching involved in lung morphogenesis positive regulation of calcineurin-NFAT signaling cascade cellular response to amino acid stimulus cellular response to nicotine cellular response to organic cyclic compound positive regulation of podosome assembly endothelial cell apoptotic process protein localization to plasma membrane necroptotic signaling pathway positive regulation of cytokine production involved in inflammatory response negative regulation of beta-amyloid clearance positive regulation of NIK/NF-kappaB signaling positive regulation of synoviocyte proliferation positive regulation of superoxide dismutase activity positive regulation of beta-amyloid formation positive regulation of protein localization to plasma membrane regulation of establishment of endothelial barrier negative regulation of bicellular tight junction assembly positive regulation of I-kappaB phosphorylation negative regulation of production of miRNAs involved in gene silencing by miRNA positive regulation of vascular smooth muscle cell proliferation positive regulation of leukocyte adhesion to arterial endothelial cell positive regulation of protein localization to cell surface positive regulation of blood microparticle formation positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of endothelial cell apoptotic process positive regulation of estradiol secretion negative regulation of extrinsic apoptotic signaling pathway in absence of ligand protein import into nucleus, translocation MAPK cascade positive regulation of cytokine production positive regulation of protein phosphorylation negative regulation of cytokine secretion involved in immune response inflammatory response I-kappaB kinase/NF-kappaB signaling extrinsic apoptotic signaling pathway via death domain receptors response to salt stress positive regulation of gene expression negative regulation of gene expression regulation of tumor necrosis factor-mediated signaling pathway negative regulation of lipid storage positive regulation of protein complex assembly positive regulation of chemokine production tumor necrosis factor-mediated signaling pathway positive regulation of NF-kappaB import into nucleus positive regulation of apoptotic process positive regulation of programmed cell death regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of MAP kinase activity negative regulation of growth of symbiont in host positive regulation of interleukin-8 biosynthetic process negative regulation of fat cell differentiation positive regulation of cell adhesion positive regulation of protein kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of smooth muscle cell proliferation positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of protein transport positive regulation of NFAT protein import into nucleus positive regulation of vitamin D biosynthetic process positive regulation of ERK1 and ERK2 cascade death-inducing signaling complex assembly positive regulation of mononuclear cell migration establishment of protein localization to plasma membrane extrinsic apoptotic signaling pathway positive regulation of leukocyte adhesion to vascular endothelial cell positive regulation of ceramide biosynthetic process regulation of endothelial cell apoptotic process