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Invitrogen
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MA1-21251 detects DP1 in human, mouse and rat samples.
MA1-21251 has been successfully used in immunofluorescence, immunohistochemistry and Western blot procedures. Immunostaining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
The MA1-21251 immunogen is recombinant full length human DP1.
DP family contains at least two members, DP1 and 2. Structurally, DP1 and 2 are relatively conserved, yet their expression appears to be tissue specific. E2F 1, a functional target for the tumor suppressor protein Rb, heterodimerizes with DP1 and forms an active E2F transcriptional complex. The interaction between members of the E2F and the DP families is mediated, in part, by a leucine repeat which is weakly conserved between the two families.
仅用于科研。不用于诊断过程。未经明确授权不得转售。