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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
MA5-15679 targets HK2 in indirect ELISA, FACS, IHC and WB applications and shows reactivity with Human samples.
The MA5-15679 immunogen is purified recombinant fragment of human HK2 expressed in E. Coli.
MA5-15679 detects HK2 which has a predicted molecular weight of approximately 102kDa.
In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686M1669; Hexokinase; hexokinase-2 muscle; OTTHUMP00000202738