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Invitrogen
HuR Monoclonal Antibody (OTI14F4)
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FIGURE: 1 / 8
HuR Antibody (MA5-25037) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of breast tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a ELAVL1 monoclonal antibody (Product # MA5-25037) at a dilution of 1:50.
Product Details
MA5-25037
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI14F4
Immunogen
Full length human recombinant protein of ELAVL1 produced in HEK293T cell
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.78 mg/mL
Amount
78 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV-like protein 1; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; Hu-antigen R; Human antigen R; HuR; unnamed protein product
Gene Aliases: ELAV1; ELAVL1; Hua; HUR; MelG
UniProt ID: (Human) Q15717
Entrez Gene ID: (Human) 1994
lncRNA-mediated post-transcriptional gene silencing
protein import into nucleus
cell proliferation
response to glucose
positive regulation of autophagy
posttranscriptional gene silencing
positive regulation of superoxide anion generation
regulation of mRNA stability
positive regulation of translation
positive regulation of autophagosome size
mRNA stabilization
protein homooligomerization
negative regulation of gene silencing by miRNA
mRNA destabilization
3'-UTR-mediated mRNA stabilization
regulation of stem cell population maintenance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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