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Invitrogen
PDE1B Monoclonal Antibody (OTI6B9)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-25649
产品规格
种属反应
Dog,
Human,
Non-human primate,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI6B9
抗原
Full length human recombinant protein of PDE1B produced in HEK293T cell
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.95 mg/mL
规格
95 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; anti-oxidant protein 2; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Cam PDE 1B; Cam PDE1B; Cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; PDE 1B; PDES 1B; Phosphodiesterase; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent
基因别名: Aop2; PDE1B; Pde1b1; PDES1B
UniProt ID: (Rat) Q01066
Entrez Gene ID: (Dog) 100856025, (Rat) 29691
regulation of neurotransmitter levels
response to amphetamine
cAMP catabolic process
signal transduction
locomotory behavior
visual learning
monocyte differentiation
cellular response to macrophage colony-stimulating factor stimulus
regulation of dopamine metabolic process
serotonin metabolic process
cGMP catabolic process
cellular response to granulocyte macrophage colony-stimulating factor stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
